Our publications relevant to current projects:
Leontovyč A., Ulrychová, L., O’Donoghue, A., Mareš, M., Vondrášek J., Marešová L., Hubálek M., Fajtová P., Chanová M., Jiang Z., Craik CS., Caffrey CR., Dvořák, J., Horn, M. SmSP2: a serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties. PLoS Neglected Tropical Diseases. 2018 Apr 20;12(4):e0006446.
Dvořák J., Horn M. Serine proteases in schistosomes and other trematodes. International Journal for Parasitology. 2018 Apr;48(5):333-344. Epub 2018 Mar 2.
Sojka D, Hartmann D, Bartošová-Sojková P, Dvořák J. Parasite Cathepsin D-Like Peptidases and Their Relevance as Therapeutic Targets. Trends in Parasitology 2016 Sep;32(9):708-23.
Dvořák J, Fajtová P, Ulrychová L, Leontovyc A, Rojo-Arreola L, Suzuki BM, Horn M, Mares M, Craik CS, Caffrey CR, O'Donoghue AJ. Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles. Biochimie 2016; 122: 99-109. (Epub 2015 Sep 26)
Horn M, Fajtová P, Rojo Arreola L, Ulrychová L, Bartosová-Sojková P, Franta Z, Protasio AV, Opavský D, Vondrášek J, McKerrow JH, Mares M, Caffrey CR, Dvořák J. Trypsin- and Chymotrypsin-like serine proteases in Schistosoma mansoni-- 'the undiscovered country'. PLoS Neglected Tropical Diseases. 2014; 8(3):e2766.